Fig. 4: Empirical curve based on the area under the curve (AUC) from 10,000 permutation.
From: Pharmacogenomics of coronary artery response to intravenous gamma globulin in kawasaki disease

X-axis is the AUC value after a random permutation of the outcome variable (medium to large coronary aneurysm, z > 5.0) based on the 12 genomic loci from FUMA in predicting the risk score of having a large aneurysm and Y-axis is the frequency. Empirical P-value (eP) is proportion of permutations resulting in a larger AUC than original data.