Table 3 The actual and principal component analysis (PCA) adjustment predicted height distribution in TWB participants (N = 78,719)
From: Polygenic height prediction for the Han Chinese in Taiwan
Male | ||||||
|---|---|---|---|---|---|---|
Model | N | Mean ± SD | Median (range) | Difference > 5% N (%)a | PCC | PCC’s SD |
Actual | ||||||
24655 | 169.47 ± 6.29 | 169.5 (112.00–200.00) | ||||
Training set | ||||||
PGS + PC1 - PC20 | 221895 | 169.47 ± 5.43 | 169.38 (127.70–196.31) | 151 (0.61%) | 0.8726 | 0.0010 |
PGS + birth year in AD + PC1 - PC20 | 221895 | 169.47 ± 5.52 | 169.38 (130.53–195.57) | 119 (0.48%) | 0.8856 | 0.0010 |
PGS + age at measurement + PC1 - PC20 | 221895 | 169.47 ± 5.52 | 169.39 (130.62–195.53) | 118 (0.48%) | 0.8857 | 0.0010 |
PGS + birth year in AD + age at measurement + PC1 - PC20 | 221895 | 169.47 ± 5.52 | 169.39 (130.58–195.55) | 117 (0.47%) | 0.8858 | 0.0010 |
Testing set | ||||||
PGS + PC1 - PC20 | 24655 | 169.48 ± 5.64 | 169.39 (138.11–201.41) | 1132 (4.59%) | 0.7573 | 0.0042 |
PGS + birth year in AD + PC1 - PC20 | 24655 | 169.48 ± 5.71 | 169.42 (139.55–199.92) | 864 (3.50%) | 0.7815 | 0.0040 |
PGS + age at measurement + PC1 - PC20 | 24655 | 169.47 ± 5.71 | 169.41 (139.66–200.07) | 867 (3.52%) | 0.7814 | 0.0040 |
PGS + birth year in AD + age at measurement + PC1 - PC20 | 24655 | 169.48 ± 5.71 | 169.41 (139.59–199.96) | 862 (3.50%) | 0.7816 | 0.0040 |
Female | ||||||
|---|---|---|---|---|---|---|
Model | N | Mean ± SD | Median (range) | Difference > 5% N (%)a | PCC | PCC’s SD |
Actual | ||||||
54064 | 157.43 ± 5.66 | 157.50 (118.50–181.50) | ||||
Training set | ||||||
PGS + PC1 - PC20 | 486576 | 157.44 ± 4.81 | 157.39 (133.26–178.97) | 387 (0.72%) | 0.8596 | 0.0007 |
PGS + birth year in AD + PC1 - PC20 | 486576 | 157.44 ± 4.92 | 157.39 (134.56–180.08) | 244 (0.45%) | 0.8778 | 0.0007 |
PGS + age at measurement + PC1 - PC20 | 486576 | 157.44 ± 4.92 | 157.38 (134.45–180.00) | 242 (0.45%) | 0.8779 | 0.0007 |
PGS + birth year in AD + age at measurement + PC1 - PC20 | 486576 | 157.44 ± 4.92 | 157.38 (134.54–180.07) | 239 (0.44%) | 0.8780 | 0.0007 |
Testing set | ||||||
PGS + PC1 - PC20 | 54064 | 157.43 ± 5.47 | 157.40 (109.07–241.61) | 6606 (12.22%) | 0.5711 | 0.0035 |
PGS + birth year in AD + PC1 - PC20 | 54064 | 157.43 ± 5.51 | 157.42 (111.06–242.96) | 5345 (9.89%) | 0.6229 | 0.0034 |
PGS + age at measurement + PC1 - PC20 | 54064 | 157.44 ± 5.52 | 157.42 (109.89–237.99) | 5360 (9.91%) | 0.6211 | 0.0034 |
PGS + birth year in AD + age at measurement + PC1 - PC20 | 54064 | 157.43 ± 5.48 | 157.42 (110.86–214.27) | 5311 (9.82%) | 0.6262 | 0.0034 |
