Fig. 1: Meta-analysis results for genome-wide association to spherical equivalent in discovery stage.

The y axis is –log10 P values for association with spherical equivalent, the x axis is chromosomes and base pair positions based on human genome build 37. The horizontal red and blue lines indicate genome-wide significance (P ≤ 5.0 × 10−8) and candidate significance (P ≤ 1.0 × 10−5), respectively. The figure was generated using R package (v. 3.4.2).