Fig. 2: The effects of GRS and diopter-hours on myopia. | npj Genomic Medicine

Fig. 2: The effects of GRS and diopter-hours on myopia.

From: Genome-wide association study identified novel loci and gene-environment interaction for refractive error in children

Fig. 2: The effects of GRS and diopter-hours on myopia.

a Interactions between GRS and diopter-hours on SE. The scatter plot represents estimated individuals’ daily diopter-hours and their corresponding SE. Each line represents the linear regression between diopter hours and SE for each stratum of GRS. b The odds ratio of myopia across strata of diopter-hours and GRS. Each point represents an odds ratio estimate and the vertical lines indicating confidence intervals. The blue, green and pink labels indicate low, moderate, and high GRS strata, respectively. The dashed horizontal line at 1.0 represents the null effect. GRS, genetic risk score; SE, spherical equivalent. The figure was generated using R package (v. 3.4.2).

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