Table 2 Global and regional volumetric brain changes and balance control changes from pre-flight to post-flight

From: Brain structural plasticity with spaceflight

     

95 % CI

 
 

N

Average pre-flight

Difference post-flight

SE of the difference

Lower

Upper

p-value

SOT5 (%)

21

84.7

−13.4

3.3

−19.8

−7.0

<0.001

SOT5-HM (%)

21

77.9

−43.1

5.0

−52.8

−33.2

<0.001

Global GM (ml)

27

611.4

−5.7

5.9

−17.3

5.9

0.34

Global WM (ml)

27

581.3

1.5

5.9

−10.1

13.1

0.80

Global CSF (ml)

27

302.7

4.2

4.5

−4.6

12.9

0.35

ICV (ml)

27

1494.9

0.8

3.0

−5.0

6.6

0.78

Pre CG (ml)

27

6.31

0.02

0.11

−0.19

0.23

0.86

Post CG (ml)

27

4.01

<0.01

0.07

−0.13

0.12

0.94

Para CG (ml)

27

1.60

0.07

0.03

0.02

0.13

0.012

Vestibular cortex ROI (μl)

27

629.5

6.9

8.5

−23.5

9.7

0.41

  1. Volumetrics were adjusted for total intracranial volume (tICV)
  2. CI confidence interval, SE standard error, GM gray matter, WM white matter, CSF cerebro spinal fluid, CG central gyrus, ROI region of interest, SOT5-HM sensory organization test 5 with head movement