Fig. 4: Magnitude effects of IOP, ICP, and TLPD on contrast sensitivity.

Losses in contrast sensitivity were plotted against experimental IOP (a), ΔIOP (b), experimental ICP (c), ΔICP (d), experimental TLPD (e) and ΔTLPD (f). a−f The magnitude of contrast sensitivity loss for saline-injected (black) and bead-injected (red) eyes under scotopic (solid circle, solid trend line) and photopic (open circle, dotted trend line) conditions is shown. There is a strong relationship between both ΔICP and ΔTLPD and the magnitude of scotopic contrast sensitivity loss, but only for bead-injected eyes. Logistic regression curve plotting the probability of scotopic contrast sensitivity loss according to ΔICP and ΔTLPD (g, h). **p < 0.01.