Fig. 6: Reduced dendritic spine density in the rodent medial prefrontal cortex 15 weeks following exposure to cosmic radiation. | npj Microgravity

Fig. 6: Reduced dendritic spine density in the rodent medial prefrontal cortex 15 weeks following exposure to cosmic radiation.

From: Red risks for a journey to the red planet: The highest priority human health risks for a mission to Mars

Fig. 6

Representative digital images of 3D reconstructed dendritic segments (green) containing spines (red) in unirradiated (0 cGy) and irradiated (5 and 30 cGy) mice brains. Multiple comparisons show that total spine numbers (left bar chart) and spine density (right bar chart) are significantly reduced after exposure to 5 or 30 cGy of 16O particles. Data are expressed as mean ± SEM. *P < 0.05, **P < 0.01 versus control; ANOVA. Adapted from Parihar et al.39. Permission to reproduce open-source figure per the Creative Commons Attribution 4.0 International License. https://creativecommons.org/licenses/by/4.0.

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