Table 2 Erythropoietic markers. Data (95% CI) for erythropoietic markers before, during, and after bed rest.

From: Six degrees head-down tilt bed rest caused low-grade hemolysis: a prospective randomized clinical trial

Measure

Bed rest study timepoint

BDC-4

HDT20

HDT49

HDT60

R1

R7

R13

R30

RBC 106/mm3

4.529 (4.393–4.665)

5.011 (4.887–5.134)

5.007 (4.834–5.179)

4.803 (4.627–4.979)

4.469 (4.322–4.615)

 

4.348 (4.180–4.516)

4.358 (4.168–4.547)**

Reticulocyte 103/µl

47.4 (39.1–55.6)

50.7 (41.2–60.3)

45.9 (38.9–52.9)

   

63.9 (55.9 – 71.9)

56.6 (48.6–64.6)**

tHb g/kg

10.9 (10.4–11.5)**

  

10.0 (9.5–10.5)**

 

9.6 (9.1–10.1)**

  

tHb g

818.2 (764.4–872.0)**

  

735.0 (673.9–796.0)**

 

723.5 (674.6–772.5)**

  

Hb g/dl

13.7 (13.4–14.0)

15.1 (14.8–15.4)

15.0 (14.6–15.5)

14.4 (13.9–14.8)

13.4 (13.0–13.8)

 

13.1 (12.7–13.5)

13.2 (12.7–13.6)

Participants Hb < 13.0 g/dl

2/20

0/20

0//20

0/20

5/20

 

9/20

7/17

EPO mUI/ml

12.2 (10.2–14.2)

8.9 (7.7–10.1)

10.1 (8.7–11.6)

   

16.3 (12.8 – 19.9)

17.8 (13.6–22.0)**

Haptoglobin g/l

1.03 (0.89–1.16)

0.99 (0.87–1.12)

1.04 (0.89–1.19)

   

1.07 (0.94–1.21)

1.10 (0.93–1.27)**

  1. Underlined values show the bed rest phase. Bold data were statistically significant from baseline (p < 0.05). **n = 17.
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