Table 3 Responses of extensor digitorum longus (EDL) muscle proteins involved in glutathione-mediated detoxification and glutathione redox reactions to microgravity (µ-g) or artificial 1-g (A1-g) exposure and/or fructo-oligosaccharide (FOS) ingestion.

From: Effects of microgravity exposure and fructo-oligosaccharide ingestion on the proteome of soleus and extensor digitorum longus muscles in developing mice

Gene symbol (accession)

µ-g & FOS (−)/A1-g & FOS (−)

µ-g & FOS (+)/A1-g & FOS (−)

A1-g & FOS (+)/A1-g & FOS (−)

Gsr (P47791)

* FC = 1.21, P = 2.6E−3

FC = 1.30, P = 1.1E−2

FC = 0.92, P = 2.0E−2

Gsto1 (O09131)

* FC = 1.30, P = 2.2E−3

* FC = 1.41, P = 1.6E−4

FC = 1.00, P = 9.8E−1

  1. The protein abundance profiles of the groups exposed to µ-g with and without FOS ingestion and the group exposed to A1-g with FOS ingestion were individually compared with that of the group exposed to A1-g without FOS ingestion. The results for the proteins, which were categorized as the related factors to glutathione metabolic process, glutathione-mediated detoxification and/or glutathione redox reactions by DAVID Bioinformatics Resources 6.8 and Ingenuity Pathway Analysis and significantly (p < 0.01) affected by µ-g exposure and/or FOS ingestion, in EDL muscles are indicated. The fold change (FC) and p value (P) of each protein are depicted. *: the significant high- or low-abundance proteins.
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