Table 3 Overview of the specifications or estimates of the different linear mixed models (LMM).

Fixed effects	Estimate (°)	Std error (°)	CI 95% (°)
Model 1: the effect of long-duration spaceflight on the otolith-mediated reflex, the OCR
Intercept	5.78	0.12	[5.55; 6.02]
Timepoint [BDC2]	0.07	0.16	[−0.24; 0.40]
Timepoint [R + 1/3]	−3.76	0.18	[−4.12; −3.40]
Timepoint [R + 4/7]	−1.96	0.18	[−2.31; −1.60]
Timepoint [R + 8/12]	0.09	0.16	[−0.22; 0.41]
Orientation [CW]	−0.15	0.04	[−0.23; −0.07]
Flight	0.14	0.06	[0.01; 0.26]
Eye_Rotation [Outer Eye]	−0.49	0.04	[−0.57; −0.41]
Timepoint [BDC2]*Flight	−0.07	0.08	[−0.21; 0.11]
Timepoint [R + 1/3]*Flight	0.50	0.09	[0.32; 0.67]
Timepoint [R + 4/7]*Flight	0.12	0.09	[−0.07; 0.31]
Timepoint [R + 8/12]*Flight	−0.07	0.08	[−0.23; 0.09]
Model 2: the OCR re-adapts to the normal gravitational level of Earth
Intercept	−0.26	0.38	[−1.01; 0.48]
Flight	1.03	0.15	[0.75; 1.32]
Orientation [CW]	−0.23	0.07	[−0.38; −0.09]
Eye_Rotation [Outer Eye]	−0.41	0.07	[−0.56; −0.27]
DaysAfterReturn	0.80	0.09	[0.63; 0.97]
DaysAfterReturn*Flight	−0.14	0.03	[−0.21; −0.07]
Model 3: the effect of previous spaceflight on the otolith-mediated OCR changes
Intercept	0.18	0.05	[0.09; 0.28]
Flight	0.19	0.03	[0.14; 0.25]
Flight >2	−0.16	0.04	[−0.24; −0.08]

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