Fig. 6: Effect of unloading on irisin serum levels.
From: Time-dependent unloading effects on muscle and bone and involvement of FNDC5/irisin axis
Figure 6 showed the trend in irisin serum levels of control mice kept in resting condition (Rest) and HU mice (Unload) for 1-2-3 and 4 weeks (a–d). Irisin serum levels were significantly reduced after 4 weeks of unloading compared to Rest mice (d). Shapiro-Wilk test and Mann-Whitney test were performed. Data are presented as box-and-whisker with median and interquartile ranges, from max to min, with all data points shown. *p < 0.05 vs Rest.
