Fig. 1: Overview of the experimental setup.
From: Gravitational effects on fibroblasts’ function in relation to wound healing
Addition of hydrocortisone (HC) or a control vehicle (PBS) to the medium was done 48 h before exposure to altered gravity levels and was followed by exposure to simulated microgravity (smg) by means of the Random Positioning Machine or hypergravity at 15 × g or 20 × g by means of the Large Diameter Centrifuge (LDC) located at ESA-ESTEC. Two additional groups were exposed to simulated microgravity intermitted with a temporary hypergravity exposure at either 15 × g T or 20 × g T after which they were placed back into simulated microgravity. Finally, 1 × g controls were placed in the center of the LDC. This figure was created with BioRender.com.
