Fig. 4: α-Tubulin and acetyl-α-tubulin architecture in 1 g flight control and µg cells. | npj Microgravity

Fig. 4: α-Tubulin and acetyl-α-tubulin architecture in 1 g flight control and µg cells.

From: Microgravity triggers ferroptosis and accelerates senescence in the MG-63 cell model of osteoblastic cells

Fig. 4: α-Tubulin and acetyl-α-tubulin architecture in 1 g flight control and µg cells.

a Large field views of α-tubulin staining (green) and nuclei (blue) in 1 g and µg cells. b Higher magnifications show the organization of the microtubules in each gravity condition: an entangled wavy fibrils pattern in 1 g cells versus a straighter structural organization in µg cells. c, d Different field views of acetyl-α-tubulin staining (green) and nuclei (blue) in 1 g and µg cells. The staining is generally limited to a few microtubules in 1 g cell. Conversely, all the cells in µg are characterized by intense staining showing the presence of acetyl-α-tubulin organized in microtubules throughout their entire cytoplasm. Scale bars are 50 µm (a and c) and 10 µm (b and d).

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