Fig. 2: Radiation affects bystander cell proliferation, GI, and carcinogenic transformation in the SMG environment. | npj Microgravity

Fig. 2: Radiation affects bystander cell proliferation, GI, and carcinogenic transformation in the SMG environment.

From: Microgravity alleviates low-dose radiation-induced non-targeted carcinogenic effects

Fig. 2

SF (a, d), MN frequency (b, e) and TF (c, f) of bystander cells co-cultured with irradiated target cells in the normal gravity or SMG environment. \(\frac{{\rm{X\; ray}}}{{\rm{Ctrl}}}\) and \(\frac{{\rm{Carbon}}}{{\rm{Ctrl}}}\) mean bystander cells without any treatment co-cultured with target cells irradiated with different doses of X-rays and carbon ions, respectively. \(\frac{{\rm{SMG}}+{\rm{X\; ray}}}{{\rm{SMG}}}\) and \(\frac{{\rm{SMG}}+{\rm{Carbon}}}{{\rm{SMG}}}\) mean bystander cells after SMG treatment co-cultured with target cells irradiated with different doses of X-rays and carbon ions after SMG. All experiments used BEAS-2B cells. Data are represented as mean ± standard, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

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