Fig. 8

Bioresorbable silicon electronics for the brain. a Schematic exploded view illustration of a bioresorbable sensor for intracranial pressure monitoring and optical image of the Si NM strain sensor, integrated at the edge of a cavity etched on the surface of a nanoporous silicon substrate (inset). Images of injection of a bioresorbable pressure senor for deep brain monitoring and of the device inserted into a hydrogel to mimic the brain environment (inset). Plots of in vivo measurements of pressure (top right) and temperature (bottom right) in the deep brain using a bioresorbable sensor and a commercial sensor as a point of comparison. Reprinted with permission from Kang et al.³² Copyright 2016 Nature Publishing Group. b Image of a 64-channel bioresorbable actively multiplexed array for electrocorticography (ECoG). Schematic illustration (top center) and optical (bottom center) images of the devices, mounted on the cerebral cortex of a rat brain. Delay map for the bandpass filtered data of epileptic spike activity (right). Reprinted with permission from Yu et al.⁹⁷ Copyright 2016 Nature Publishing Group