Fig. 4: Transdermal HA delivery of CNFs-based adhesive based on structure and concentration. | npj Flexible Electronics

Fig. 4: Transdermal HA delivery of CNFs-based adhesive based on structure and concentration.

From: Skin-adaptive nanofiber-based adhesive electronics with octopus-like 3D suction cups for enhanced transdermal delivery

Fig. 4

a Delivery depth of rhodamine B-tagged HA (15 wt%) through pigskin at different application times (10, 20, and 30 min) and structural types (blue columns: OIA, green columns: Hole, gray columns: Flat); N = 10. b Confocal microscopy analysis of rhodamine B-tagged HA diffusion through pigskin at different application times (10, 20, and 30 min). c Changes in the diffusion coefficient of rhodamine B in pigskin based on application time and structural type (blue line: OIA, green line: Hole, gray line: Flat). d Delivery depth, e confocal microscopy analysis, and f diffusion coefficient variation of rhodamine B-tagged HA at various concentrations (1, 5, 10, 15, and 20 wt%) through pigskin for different structural types (blue columns: OIA, green columns: Hole, gray columns: Flat) at a fixed application time of 20 min; N = 10. Statistical analysis was done by One-way ANOVA test followed by Turkey’s Multi-comparison test. *P < 0.05, **P < 0.01, and ***P < 0.001 versus OIA. n.s., not significant.

Back to article page