Fig. 6: Chemical sensors in biomedical applications.
From: Advances and perspectives in fiber-based electronic devices for next-generation soft systems
a Schematic of the wireless sensing platform employing an implantable fiber sensor for real-time monitoring of Homovanillic (HVA) levels in blood. (MIP: Molecularly imprinted polymer; PVB: Polyvinyl butyral; PDMS: Polydimethylsiloxane; CNT: Carbon nanotube) b Comparison of calibration data for HVA from collected blood samples with on-body readings from the HVA fiber sensor. The data obtained from the HVA fiber sensor matched well with ex situ measurements of blood samples by a commercial ELISA kit with an accuracy of up to 97.8%. a, b Reprinted with permission30. Copyright 2024, American Chemical Society. c Design of the pH-sensing suture, featuring a core supporting suture thread, a PANI-coated working fiber electrode, and an Ag/AgCl-coated reference fiber electrode. d Photograph before (left) and after (right) the application of the pH-sensing suture to the dorsal wound. e pH monitoring depending on the presence or absence of dexamethasone (DEX) treatment. Over 3weeks of observation, the pH level in the AD models without dexamethasone treatment gradually decreased, but this decline was further accelerated with dexamethasone treatment. c–e Reprinted with permission167. Copyright 2024, WILEY-VCH Verlag GmbH & Co. KgaA, Weinheim. f Schematic illustration of the three-electrode glucose sensor integrated into an elastic textile. g Schematic illustration of the fiber working electrode, with Prussian blue (PB) and glucose oxidase (Gox) for selective glucose detection. (SEBS: styrene-ethylene/butylene-styrene) h Photographs of the stretchable glucose sensor sutured into an elastic sock. f–h Reprinted with permission168. Copyright 2019, American Chemical Society.
