Table 1 Baseline characteristics for unilateral patientsa,b.
From: Long-term Parkinson’s disease quality of life after staged DBS: STN vs GPi and first vs second lead
Variable (mean ± SD (N)) | STN (70) | GPi (121) | STN vs GPi |
|---|---|---|---|
Age | 65.07 ± 7.88 (70) | 66.09 ± 7.71 (120) | p = 0.39 |
Age at disease onset | 53.57 ± 10.23 (65) | 54.08 ± 9.40 (102) | p = 0.99 |
Disease duration | 11.51 ± 6.20 (65) | 11.83 ± 5.69 (102) | p = 0.72 |
Gender (male no./no.) | 57/70 | 85/120 | p = 0.15 |
UPDRS-I | 2.81 ± 2.35 (63) | 2.49 ± 1.98 (108) | p = 0.53 |
UPDRS-II | 15.91 ± 5.96 (64) | 15.73 ± 6.17 (111) | p = 0.85 |
UPDRS-III off-med | 37.34 ± 11.78 (65) | 38.27 ± 11.03 (114) | p = 0.60 |
UPDRS-III off-med contralateral tremor | 4.15 ± 2.46 (65) | 3.09 ± 2.16 (114) | p < 0.01 |
UPDRS-III off-med contralateral rigidity | 3.45 ± 1.53(65) | 3.57 ± 1.44 (114) | p = 0.77 |
UPDRS-III off-med contralateral bradykinesia | 7.52 ± 2.62 (65) | 7.50 ± 2.56 (114) | p = 0.96 |
UPDRS-III off-med PIGD | 4.29 ± 2.62 (65) | 5.42 ± 3.07 (114) | p < 0.01 |
LEDD | 1439 ± 936 (68) | 1407 ± 822 (118) | p = 0.85 |
Berg balance scale | 51.65 ± 2.91 (26) | 50.30 ± 5.29 (73) | p = 0.37 |
TUG | 9.55 ± 1.83 (31) | 10.89 ± 11.83 (79) | p = 0.55 |
Dopamine responsivenessc | −32.32 ± 23.89 (62) | −36.24 ± 18.03 (109) | p = 0.46 |
MMSE | 28.04 ± 2.10 (24) | 28.67 ± 1.73 (30) | p = 0.19 |
SWAL-QOL | 85.10 ± 10.91 (19) | 80.56 ± 11.27 (24) | p = 0.17 |
Anxiety | 17.67 ± 7.04 (12) | 15.00 ± 9.53 (40) | p = 0.24 |
Depression | 10.52 ± 6.43 (31) | 11.04 ± 7.45 (76) | p = 0.95 |
Total PDQ | 30.80 ± 15.25 (70) | 31.73 ± 15.22 (121) | p = 0.47 |
Mobility | 36.34 ± 23.02 (70) | 44.49 ± 27.89 (121) | p < 0.05 |
ADL | 39.29 ± 21.41 (70) | 36.00 ± 21.66 (121) | p = 0.32 |
Emotional well-being | 29.46 ± 19.21 (70) | 30.11 ± 20.22 (121) | p = 0.85 |
Stigma | 30.00 ± 26.03 (70) | 25.57 ± 22.20 (121) | p = 0.34 |
Social support | 10.65 ± 13.69 (70) | 15.98 ± 19.58 (121) | p = 0.17 |
Cognition | 28.31 ± 18.33 (70) | 29.11 ± 20.14 (121) | p = 0.95 |
Communication | 27.02 ± 21.31 (70) | 29.99 ± 21.16 (121) | p = 0.34 |
Bodily discomfort | 45.36 ± 22.04 (70) | 42.29 ± 22.84 (121) | p = 0.44 |
