Table 2 Independent tests between PD and HCs (significant test results are printed in bold).
Independent tests (PD–control) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Baseline | Follow-up | |||||||||||||
Mean difference | PD mean ± SD (n) | Control mean ± SD (n) | T test | Mann–Whitney | Fisher’s test | FDR | Mean difference | PD mean ± SD (n) | Control mean ± SD (n) | T test | Mann–Whitney | Fisher’s test | FDR | |
tdc-gene abundance | ||||||||||||||
tdc-gene abundance (outliers removed) | −7.4E−07 | 1.5E−6 ± 1.3E−6 (55) | 2.2E−6 ± 2.2E−6 (54) | 0.177 | n.a. | 6.47E−07 | 3.8E−6 ± 2.6E−6 (57) | 3.1E−6 ± 2.7E−6 (55) | 0.057 | n.a. | ||||
Gastrointestinal symptoms | ||||||||||||||
Wexner total score | 2.73 | 5.66 ± 4.01 (67) | 2.92 ± 2.61 (65) | 2.4E−05 | 2.4E−05 | 3.99 | 6.37 ± 4.63 (67) | 2.38 ± 2.58 (65) | 5.9E−09 | 1.2E−08 | ||||
Rome III (constipation and defecation) | 4.40 | 7.37 ± 5.96 (67) | 2.97 ± 3.60 (65) | 1.2E−06 | 2.4E−06 | 4.60 | 7.36 ± 5.17 (67) | 2.75 ± 3.60 (65) | 1.3E−08 | 1.3E−08 | ||||
Medication | ||||||||||||||
Use of anacidic (yes/no) | −2% | 6/61 (67) | 7/58(65) | 0.777 | 0.777 | 6% | 4/63 (67) | 0/65 (65) | 0.119 | 0.238 | ||||
Use of anticholinergic (yes/no) | 9% | 6/61 (67) | 0/65 (65) | 0.028 | 0.056 | 3% | 3/64 (67) | 1/64 (65) | 0.619 | 0.619 | ||||
