Fig. 4: Association between GABAergic response to dopamine agonist therapy and thalamic dopamine receptor availability. | npj Parkinson's Disease

Fig. 4: Association between GABAergic response to dopamine agonist therapy and thalamic dopamine receptor availability.

From: Dopamine-induced changes to thalamic GABA concentration in impulsive Parkinson disease patients

Fig. 4

Scatter plot showing the relationship between the thalamic GABAergic response to DAA medication (ΔGABA) and thalamic [18F]fallypride BPND in ICB+ and ICB− patients, adjusting for age. Dark center lines indicate fitted lines, while lighter colored bands denote confidence bands. This relationship appears to differ between ICB+ and ICB− patients (GLM: Thalamic ΔGABA ~ thalamic BPND + ICD status + thalamic BPND*ICD status + age, p-value for the interaction term thalamic BPND*ICD status: p = 0.051).

Back to article page