Fig. 3: Processed fragments of active neuropeptides elevated in LID.
From: Basal ganglia neuropeptides show abnormal processing associated with L-DOPA-induced dyskinesia
MALDI MS images of a des-tyrosine dynorphin neuropeptides, Dyn A (2-8) and α-neoendorphin (2-10), b processed substance P peptides (1-9) and (1-7), and c PENK-derived peptide sequences, PENK (199-207) and PENK (219-227) without known biological functions. All images are RMS-normalized, and intensities are log-transformed and indicated with a rainbow color scale, scaled to specific percentages as annotated below each MALDI MS image. Scale bars, 5 mm; lateral resolution, 100 μm.
