Table 3 Post hoc analysis of scores of screening tests and in-depth neuropsychological evaluations reported for all groups of patients.

From: Optimization of cognitive assessment in Parkinsonisms by applying artificial intelligence to a comprehensive screening test

Variable

PD

MSA

PSP

VP

p-value PD versus MSA

p-value PD versus PSP

p-value PD versus VP

p-value MSA versus PSP

p-value MSA versus VP

p-value PSP versus VP

MMSE

27.2 ± 2.3

26.2 ± 2.1

26.2 ± 3.5

26.8 ± 2.9

0.052

0.54

0.99

0.95

0.43

0.96

FAB

14.4 ± 2.7

13.8 ± 2.2

11.6 ± 3.9

13.5 ± 3.0

0.60

<0.0001

0.21

0.25

1.00

0.27

MoCA

23.4 ± 3.6

21.9 ± 3.7

20.5 ± 4.9

21.8 ± 3.7

0.13

0.003

0.057

0.97

1.00

0.92

CoMDA

65.1 ± 7.2

61.9 ± 6.4

58.1 ± 10.6

62.1 ± 8.2

0.060

0.0005

0.10

0.94

1.00

0.62

WCST

73.2 ± 36.7

68.9 ± 34.2

90.0 ± 22.1

77.5 ± 35.5

      

Stroop test E

5.2 ± 7.6

3.2 ± 4.6

11.3 ± 8.4

11.3 ± 9.1

0.98

0.00031

<0.0001

0.003

0.001

1.00

Stroop test T

20.6 ± 13.0

25.6 ± 13.5

29.7 ± 26.4

22.8 ± 20.5

      

TMT-A

44.3 ± 46.6

61.7 ± 35.6

70.0 ± 65.5

79.8 ± 88.7

0.016

0.17

0.010

0.99

1.00

1.00

TMT-B

126.3 ± 100.2

172.2 ± 79.8

161.6 ± 107.3

186.1 ± 123.6

0.014

0.42

0.024

0.96

1.00

1.00

TMT B-A

89.1 ± 81.8

112.3 ± 64.5

123.3 ± 87.1

132.1 ± 99.3

0.12

0.20

0.09

1.00

1.00

1.00

RAVLT-e

43.1 ± 10.2

44.6 ± 9.8

38.8 ± 8.3

40.9 ± 8.3

0.96

0.08

0.54

0.10

0.43

0.93

RAVLT-delayed recall

8.7 ± 3.2

9.3 ± 3.1

7.5 ± 2.9

7.8 ± 2.8

0.80

0.16

0.28

0.08

0.14

1.00

ROCF-c

29.3 ± 6.5

26.2 ± 6.1

19.3 ± 9.3

26.5 ± 8.1

0.022

<0.0001

0.11

0.28

0.95

0.014

ROCF-dr

14.9 ± 5.7

14.8 ± 6.3

11.8 ± 6.9

13.8 ± 4.5

      

CF

43.5 ± 9.5

38.9 ± 9.7

30.9 ± 6.7

37.5 ± 8.6

0.18

<0.0001

0.003

0.023

1.00

0.044

PF

32.5 ± 10.5

25.2 ± 9.8

19.3 ± 7.6

25.8 ± 9.4

0.006

<0.0001

0.002

0.33

1.00

0.10

  1. PD Parkinson’s disease, MSA multi system atrophy, PSP progressive supranuclear palsy, VP vascular parkinsonism, MMSE mini-mental state examination, FAB frontal assessment battery, MoCA montreal cognitive assessment, CoMDA cognitive screening in movement disorders assessment, WCST Wisconsin card sorting test, Stroop Test E stroop test errors score, Stroop Test T Stroop test time-in-seconds score, TMT trial making test, RAVLT Ray auditory verbal learning test, ROCF Rey–Osterrieth complex figure test, CF categorical fluency, PF phonemic fluency, PD Parkinson’s disease, MSA multi system atrophy, PSP progressive supranuclear palsy, VP vascular parkinsonism.
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