Table 2 Results of PET neuroimaging analyses.

From: Longitudinal trimodal imaging of midbrain-associated network degeneration in Parkinson’s disease

Modality [contrast]

Region

MNI coordinates

Statistics

Cluster size

x/y/z

t-value

p-value (FWE)

FDG-PET

     

 [BL < HC]

Left midbrain

−12/−20/−20

4.525

0.028

35

 [FU < HC]

Bilateral midbrain

−6/−20/−18

5.55

<0.001

227

 [FU < BL]

Left midbrain

−8/−10/−16

4.70

0.045

22

FDOPA PET

     

 [BL < HC]

Left putamen

−28/−8/−6

5.40

0.012

187

 

Right putamen

28/−8/2

5.37

0.017

155

 [FU < HC]

Left putamen

−28/−14/−2

7.69

0.003

362

 

Right putamen

28/−10/2

8.59

0.009

228

 

Right caudate

16/6/14

4.33

0.033

99

 [FU < BL]

Right caudate

8/12/−2

9.73

0.001

220

  1. Statistical details of PET analyses by contrast and modality. All t-values were calculated using SPM12. For FDG-PET, p-values after small-volume-correction for midbrain and for FDOPA PET after small-volume-correction for striatum are shown, respectively.
Back to article page