Fig. 1: Gut and oral microbial community structure based on 16 S rRNA gene sequencing.
From: Oral and gut dysbiosis leads to functional alterations in Parkinson’s disease
a, b Principal coordinates analysis based on the Bray-Curtis dissimilarity between Parkinson’s disease (PD) and healthy controls in a stool and b oral samples. c, d Phylum-level bar charts of PD and HCs in the c stool and d oral samples. e, f Comparison of the e gut microbiome and f oral microbiome between PD and HCs using genus-level LEfSe analysis. The top 10 genera based on the LDA score in the PD and control groups are shown. The cut-off value for oral LDA effect size was set at 2.0. LLKB (Lachnospiraceae; LLKB01000001), PAC001043 (Lachnospiraceae, AJ576336), PAC001032 (Lachnospiraceae, unpublished), PAC001115 (Christensenellaceae, HQ716403) PAC000661 (Oscillospiraceae; JN713389) PAC002046 (Lachnospiraceae, GQ897562), and Eubacterium_g23 (Oscillospiraceae, GQ502529) were the phylotype genera (Family, NCBI accession number).
