Fig. 7: Comparison of outcomes for a screening-adapted version of the PREDIGT Score (Model 2) to separate Parkinson’s patients from healthy controls in DeNoPa. | npj Parkinson's Disease

Fig. 7: Comparison of outcomes for a screening-adapted version of the PREDIGT Score (Model 2) to separate Parkinson’s patients from healthy controls in DeNoPa.

From: Evaluation of the PREDIGT score’s performance in identifying newly diagnosed Parkinson’s patients without motor examination

Fig. 7

Box plots illustrate the degree of classification, as depicted by AUC values for Step 1 (PREDIGT Questionnaire score only) and Step 2 (score for one of seven objective test results) and their combination, as color-coded in the inset). The box represents the median and the two middle quartiles (25–75%). Note, for RBD SQ, the largest combined AUC value was equal to the corresponding AUC of Step 1. Therefore, we placed extra green dots on top of the corresponding boxplot. Because of missing data, especially missing CSF α-synuclein or tau levels, sample sizes in these tests were not identical. Therefore, AUC values of Step 1 (in black) were not identical for the seven tests. AUC area under the ROC curve, GDS Geriatric Depression Scale, BDI Beck’s Depression Inventory, MADRS Montgomery-Asberg Depression Scale, RBD REM sleep behavior disorder Score Sheet, CSF cerebrospinal fluid test.

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