Fig. 6: Significant (p < 0.0001) negative correlation between αSyn T:M ratio and pSer129 phosphorylation. | npj Parkinson's Disease

Fig. 6: Significant (p < 0.0001) negative correlation between αSyn T:M ratio and pSer129 phosphorylation.

From: Parkinson-causing mutations in LRRK2 impair the physiological tetramerization of endogenous α-synuclein in human neurons

Fig. 6

Each dot represents a neuronal sample for which both the pSer129 level and the T:M ratio of αSyn was quantified (without any inhibitor treatment). WT controls (corrected lines also without inhibitor treatment) were normalized to 1 for both ratios (red dotted lines).

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