Fig. 2: Nigral glucose metabolism in patients with Parkinson’s disease.
From: Nigral glucose metabolism as a diagnostic marker of neurodegenerative parkinsonian syndromes

a Boxplots of mean normalized [18F]FDG uptake of the substantia nigra in patients with high and low Parkinson’s disease-related pattern (PDRP) expression in comparison to controls. Squares and triangles indicate healthy controls and control patients, respectively. Dots represent individual patients’ values. Centerline, median; box limits, upper and lower quartiles; whiskers, 1.5x interquartile range; points, outliers. Significance threshold: ****p < 0.0001. b Receiver operating characteristics curve (ROC) for both groups. Areas under the ROC curves (AUC) and their 95%-confidence intervals (in parenthesis) are given. PD Parkinson’s disease.