Fig. 3: Reduced dopamine terminal in FTPD patients with C9orf72 expansion. | npj Parkinson's Disease

Fig. 3: Reduced dopamine terminal in FTPD patients with C9orf72 expansion.

From: Involvement of striatal motoric subregions in familial frontotemporal dementia with parkinsonism harboring the C9orf72 repeat expansions

Fig. 3: Reduced dopamine terminal in FTPD patients with C9orf72 expansion.

DTBZ-PET/CT imaging of the VMAT2 distribution in the FTDP patient (III-6) with C9orf72 expansion and controls (n = 6). The same slice is presented for all participants. White arrows indicate obvious dopamine decline of the bilateral striatum in the patient. Note the symmetric decline of vesicular transporter availability without a posterior-to anterior gradient.

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