Table 4 Feature component accuracy of 12-month MDS-UPDRS total meta-prediction.
From: Genetically-informed prediction of short-term Parkinson’s disease progression
PPMI train-test split | PDBP independent test | |||
|---|---|---|---|---|
ROC AUC | PR AUC | ROC AUC | PR AUC | |
Full meta-prediction | 077 ± 0.04 | 0.76 ± 0.04 | 0.74 ± 0.05 | 0.73 ± 0.05 |
No genetics | 0.66 ± 0.04 | 0.68 ± 0.04 | 0.66 ± 0.05 | 0.66 ± 0.05 |
No physician exam | 0.67 ± 0.04 | 0.71 ± 0.04 | 0.69 ± 0.05 | 0.71 ± 0.05 |
No surveys | 0.72 ± 0.04 | 0.72 ± 0.04 | 0.72 ± 0.05 | 0.72 ± 0.05 |
No imaging | 0.73 ± 0.04 | 0.73 ± 0.04 | - | - |
