Table 3 The risk of Parkinson’s disease according to the diabetes severity score.

From: A nationwide cohort study on diabetes severity and risk of Parkinson disease

 

Total

Events (n)

Incidence rate (per 1000 person-years)

Model 1

Model 2

Total population

0

1,221,120

5378

0.640

1 (ref.)

1 (ref.)

1

583,678

4667

1.153

1.22 (1.17, 1.27)

1.09 (1.04, 1.15)

2

332,552

3485

1.527

1.48 (1.41, 1.54)

1.28 (1.22, 1.35)

3

153,646

2141

2.076

1.84 (1.75, 1.93)

1.55 (1.46, 1.65)

4

55,942

1052

2.927

2.43 (2.28, 2.60)

1.96 (1.82, 2.11)

5

13,663

282

3.385

2.69 (2.39, 3.04)

2.08 (1.83, 2.36)

6

1471

41

4.846

3.67 (2.70, 4.99)

2.78 (2.05, 3.79)

Men

0

769,185

2833

0.538

1 (ref.)

1 (ref.)

1

328,400

2236

0.990

1.22 (1.15, 1.29)

1.09 (1.01, 1.17)

2

176,952

1581

1.320

1.44 (1.35, 1.53)

1.24 (1.15, 1.35)

3

75,135

905

1.837

1.77 (1.64, 1.91)

1.48 (1.36, 1.63)

4

25,592

426

2.682

2.35 (2.12, 2.61)

1.89 (1.69, 2.12)

5

5964

105

3.047

2.57 (2.11, 3.12)

1.98 (1.61, 2.42)

6

598

13

3.986

3.24 (1.88, 5.58)

2.44 (1.41, 4.22)

Women

0

451,935

2545

0.81148

1 (ref.)

1 (ref.)

1

255,278

2431

1.35926

1.22 (1.15, 1.29)

1.10 (1.02, 1.19)

2

155,600

1904

1.75594

1.50 (1.41, 1.59)

1.32 (1.23, 1.42)

3

78,511

1236

2.29444

1.88 (1.75, 2.01)

1.62 (1.49, 1.75)

4

30,350

626

3.12195

2.47 (2.26, 2.70)

2.02 (1.83, 2.23)

5

7699

177

3.62248

2.76 (2.37, 3.22)

2.17 (1.85, 2.54)

6

873

28

5.3852

3.93 (2.71, 5.71)

3.02 (2.08, 4.40)

  1. Model 1: adjusted for age and sex.
  2. Model 2: adjusted for age, sex, BMI, alcohol drinking, smoking, regular exercise, hypertension, dyslipidemia, and depression.