Fig. 4: Observed therapeutic windows and side effects for optimal and non-optimal current administration.

Lollipop charts denoting therapeutic windows (i.e., minimal distance in mA from observed clinical effect to observed side effect; y-axis in top panel) observed when undergoing different contact orientations of STN-DBS and reported side effects (y-axis in bottom panel). The x-axis represents the number of subjects (N) and is fixed for all charts. Reported side effects included paresthesia (1), oculomotor disturbances (2), dizziness (3), visual impairment (4), speech disturbances (5), bradydiadochokinesis (6), muscle contractions (7) and nausea (8).