Fig. 2: Interval timing variability improves in VTA dopamine-depleted mice treated with terazosin. | npj Parkinson's Disease

Fig. 2: Interval timing variability improves in VTA dopamine-depleted mice treated with terazosin.

From: Glycolysis-enhancing α1-adrenergic antagonists modify cognitive symptoms related to Parkinson’s disease

Fig. 2

a Cumulative distribution function of switch times. b Switch time coefficient of variability (CV) and c mean switch time. Data from 10 VTA Vehicle mice treated with dimethyl sulfoxide (DMSO; in black), 8 VTA 6-hydroxydopamine (6-OHDA) mice treated with DMSO (in red), and 11 VTA 6-OHDA mice treated with terazosin (TZ; in green). Each dot represents a single mouse, and the horizontal line represents the median value. All data presented are approximately 16 days post-surgery and normalized according to pre-surgical behavior. * p < 0.05.

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