Table 1 Summary of variants in NBIA related genes with higher frequency in PD cases versus controls, SNP = Single Nucleotide Polymorphism, p = P-value.

From: Exploring the genetic and genomic connection underlying neurodegeneration with brain iron accumulation and the risk for Parkinson’s disease

SNP

Gene

p (AMP-PD)

p (UKB)

Cohort

chr1:16988161:T:A

ATP13A2

0.147

–

AMP

chr1:16996487:G:A

ATP13A2

–

0.024

UKB

chr1:17000494:G:A

ATP13A2

0.502

–

AMP

chr1:17005754:G:A

ATP13A2

0.264

–

AMP

chr3:149183513:C:T

CP

0.067

0.887

AMP

chr3:149198448:T:A

CP

–

0.047

UKB

chr3:149199783:G:A

CP

0.648

0.260

AMP

chr3:149206202:T:A

CP

–

0.427

UKB

chr16:74719154:G:A

FA2H

–

0.024

UKB

chr16:74774524:C:T

FA2H

0.824

0.985

AMP

chr16:74774662:G:C

FA2H

0.875

–

AMP

chr19:29702747:T:C

C19orf12

–

0.609

UKB

chr19:29702977:C:A

C19orf12

0.875

–

AMP

chr19:29702977:C:G

C19orf12

0.264

–

AMP

chr19:29708268:G:A

C19orf12

–

0.024

UKB

chr19:48966341:G:T

FTL

0.875

–

AMP

chr20:3889237:A:T

PANK2

–

0.694

UKB

chr20:3907997:A:G

PANK2

0.114

–

AMP

chr20:3910812:A:G

PANK2

0.439

–

AMP

chr20:3912486:T:A

PANK2

–

0.024

UKB

chr20:3912490:D:3

PANK2

–

0.199

UKB

chr20:3918695:G:A

PANK2

0.439

0.106

AMP

chr22:38113560:C:T

PLA2G6

–

0.427

UKB

chr22:38126390:T:C

PLA2G6

0.875

0.069

AMP

chr22:38132881:C:T

PLA2G6

0.467

0.523

AMP

chr22:38132917:C:T

PLA2G6

0.264

–

AMP

chr22:38133007:G:A

PLA2G6

0.875

–

AMP

chr22:38143275:C:T

PLA2G6

0.875

–

AMP

chr22:38169326:G:A

PLA2G6

0.151

0.514

AMP

  1. Bold entries indicate statistical significance at a nominal p value < 0.05.
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