Fig. 5: Probabilistic maps of the LC NM content in HC, iPD, and LRRK2-PD groups.

a 2D-slice axial visualization of the probabilistic maps, b 3D volumetric renders, and c Colorbar for the normalized NM content per voxel. Average brainstem mask is shown in gray. The probabilistic map shows the voxels for which most subjects contain NM (warm colors) and the voxels for which few subjects contain NM (cold colors). To improve visual quality, all maps were spatially upsampled by a factor of four using bicubic interpolation.