Fig. 2: Subtstantia nigra pars reticulata histological and electrophysiological results.
From: Altered parabrachial nucleus nociceptive processing may underlie central pain in Parkinson’s disease
a Location of recording sites within the SNr for the Sham (blue dots), Partial DA lesion (orange dots) and Total DA lesion (red dots) groups. b C. Histograms of the means (±SEM) of firing rate (left), firing rate measured during the control (cont) and noxious stimulation period (stim) (middle) and nociceptive response magnitude (right) measured in the Sham (blue), Partial (orange) and Total (red) DA lesion groups. Note that the introduction of the noxious stimulation induced a firing rate increase in the three experimental groups. c Peristimulus histograms showing individual cases of different types of phasic noxious stimulation-evoked responses in the SNr. The red vertical line indicates the onset time of the noxious footshock. The n associated with each histogram indicates the number of cases exhibiting that class of response.
