Table 2 Purdue Pegboard test scores.

From: Distinct cortical and subcortical predictors of Purdue Pegboard decline in Parkinson’s disease and atypical parkinsonism

 

PD

(mean ±1 SD)

PSP

(mean ±1 SD)

MSA

(mean ±1 SD)

HC

(mean ±1 SD)

Diagnosis

(p-value)

Time

(p-value)

Time * diagnosis

(p-value)

Dominant

Visit 1

10.26 ± 2.504

6.590 ± 2.953

6.478 ± 2.761

12.77 ± 2.072

<0.001***

0.660

<0.001***

Visit 2

9.683 ± 2.581

4.615 ± 2.952

5.304 ± 2.961

13.13 ± 2.631

Change

−0.579 ± 1.922

−1.974 ± 2.611

−1.174 ± 2.229

0.358 ± 2.497

<0.001***

-

-

Non-dominant

Visit 1

10.10 ± 2.507

6.179 ± 2.964

6.174 ± 3.128

12.83 ± 1.816

<0.001***

0.833

0.001**

Visit 2

9.604 ± 2.715

4.410 ± 2.890

5.043 ± 3.282

12.77 ± 1.958

Change

−0.494 ± 1.901

−1.769 ± 2.757

−1.130 ± 1.984

−0.057 ± 1.748

0.006**

-

-

Both hands

Visit 1

15.84 ± 4.847

8.718 ± 4.599

9.870 ± 4.770

20.70 ± 3.555

<0.001***

0.793

<0.001***

Visit 2

14.57 ± 4.791

5.923 ± 4.498

6.957 ± 5.183

21.58 ± 3.845

Change

−1.268 ± 3.527

−2.795 ± 4.231

−2.913 ± 3.088

0.887 ± 3.625

<0.001***

-

-

Assembly

Visit 1

18.54 ± 5.377

10.69 ± 5.172

11.48 ± 5.526

26.77 ± 6.381

<0.001***

0.549

0.005**

Visit 2

18.24 ± 5.887

7.641 ± 4.782

8.696 ± 6.108

26.15 ± 6.320

Change

−0.305 ± 4.057

−3.051 ± 4.883

−2.783 ± 4.991

−0.623 ± 4.919

0.02*

-

-

  1. Mean scores (±1 SD) for each Purdue Pegboard task: dominant hand, non-dominant hand, both hands together, and the assembly task for baseline (Visit 1), the 1-year follow-up (Visit 2), and the change (Visit 2 − Visit 1). The main effect of diagnosis, time, and the interaction between time and diagnosis between Visit 1 and Visit 2. Age, site, MOCA baseline score, and sex were included as covariates. Significance indicated by *p < 0.05, **p < 0.01, and ***p < 0.001.
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