Table 2 Women’s health questionnaire responses.

From: Association of women-specific health factors in the severity of Parkinson’s disease

 

Total (n = 304) n (%)

My PD onset started…a

  While I was still having regular periods

52 (17.5)

  While I was going through perimenopause

26 (8.8)

  One year or more after my last menstrual period

219 (73.7)

Are you still menstruatinga

  Yes

25 (8.3)

  No

278 (91.7)

Have you ever been diagnosed with Premenstrual Syndrome (PMS)a

  Yes

34 (11.2)

  No

269 (88.8)

Are you perimenopausal?a

  Yes

18 (6.1)

  No

277 (93.9)

Has your doctor checked to see if your hormone levels have changed for perimenopause?a

  Yes

8 (44.4)

  No

10 (55.6)

Have you experienced menopause?a

  Yes

264 (88.0)

  No

36 (12.0)

Menses-related history

 Did/do you notice that PD symptoms improved at any part of the menstrual cycle?a

  Yes

7 (9.3)

  No

68 (90.7)

 When did/do you notice that PD symptoms improved? (check all apply)

  In the 1–7 days before my period started

1 (0.33)

  During, while I was bleeding

1 (0.33)

  In the 1–7 days after I stopped bleeding

4 (1.3)

  In the middle of my cycle, with ovulation

1 (0.33)

  None

1 (0.33)

 When did you notice with symptoms worsening around menses? (check all apply)

  Medication felt less effective

8 (2.6)

  Higher doses of meds were required to maintain function

4 (1.3)

  More off/irregular frequency periods

10 (3.3)

  N/A

32 (10.5)

  Don’t recall

33 (10.9)

Surgery history

 I have experienced…(check all apply)

  Total hysterectomy (removal of uterus, cervix, ovaries, Fallopian tubes, and surrounding structures)

48 (15.8)

  Oophorectomy (surgical removal of one/unilateral or both/bilateral ovaries)

25 (8.2)

  Mastectomy

9 (3.0)

  None

193 (63.5)

  Partial hysterectomy (just uterus)

33 (10.9)

Hormone-related History

 Did you start hormone replacement therapy (HRT) within the first 2 years of menopause or after receiving a hysterectomy?a

  Yes

84 (29.0)

  No

206 (71.0)

 What type of HRT have you tried?

  Estrogen

37 (12.2)

  Progesterone/Progestin

10 (3.3)

  Estrogen and progesterone combination

38 (12.5)

 Prior to being diagnosed with PD did you use any of these types of birth control?

  Pill

206 (67.8)

  Hormonal IUD

18 (5.9)

  Copper IUD

34 (11.2)

  Tubal ligation

35 (11.5)

  Essure

2 (0.66)

  Patch

4 (1.3)

  None of these

67 (22.0)

  Other

33 (10.9)

Pregnancy-related experiences

 I have experienced: (check all apply)

  In vitro fertilization

6 (2.0)

  C-section

60 (19.7)

  Vaginal birth

188 (61.8)

  Having children prior to PD diagnosis

225 (74.0)

  Having children after PD diagnosis

1 (0.33)

  No children

62 (20.4)

 Did you experience difficulties with:

  Conceiving (fertility)

42 (13.8)

  Childbirth

35 (11.5)

  Pregnancy (reaching full birth)

32 (10.5)

  None

206 (67.8)

 Did you have any of the following experiences prenatally, perinatally, or postnatally? (check all apply)

  Eclampsia or pre-eclampsia

15 (4.9)

  Diabetes during pregnancy

7 (2.3)

  Viral infection

6 (2.0)

  Bacterial infection

11 (3.6)

  Depression/anxiety during pregnancy

11 (3.6)

  Postpartum Depression

27 (8.9)

  Flair up migraines

20 (6.6)

  None

209 (68.8)

 Did you breastfeed?a

  Yes

189 (63.4)

  No

50 (16.8)

  N/A

59 (19.8)

Hormonal/autoimmune disorders

 Have you ever been diagnosed with any of these disorders?

  Polycystic Ovarian Syndrome

17 (5.6)

  Hypothyroidism

54 (17.8)

  Hyperthyroidism

19 (6.3)

  Diabetes Type I

0 (0.0)

  Diabetes Type II

15 (4.9)

  Lupus

1 (0.33)

  Rheumatoid arthritis

4 (1.3)

  Migraines (no aura)

39 (12.8)

  1. aData not available for all subjects. Missing values: pd_onset = 7; still_menstruating = 1; diagnosed_with_pms = 1; perimenopause = 9; hormone_levels_for_perimenopause = 286; experience_of_menopause = 4; symptoms improved menstrual cycle = 3; hormone_replacement_therapy = 14; breastfeeding = 6.