Table 3 Inclusion criteria.
From: Focused ultrasound thalamotomy for tremor treatment impacts the cerebello-thalamo-cortical network
TDPD | ET |
|---|---|
1) Tremor dominant and postural instability/gait difficulty ratio>1.15 in the medicated [ON] state. 2) ≥3 in the affected hand/arm, as measured by the medicated [ON] UPDRS question #20, or a postural/action tremor≥2 for question #21. Patients with bilateral appendicular tremor were included. 3) Substantial tremor-induced disability despite medical treatment, as determined by a Fahn-Tolosa-Marin Clinical Rating Scale for Tremor (CRST) score≥2 in any one of the items 16–23 from the Disability subsection of the CRST. 4) Stable medication for 30 days prior to study entry. | 1) Inadequate response to one or two medications, per local standards. An inadequate response includes poor response to the drug, or the development of side effects. 2) Postural or intention tremor score≥2 (CRST) in the dominant hand or arm, while stable on medication. Patients with bilateral appendicular tremor were included. 3) Substantial tremor-induced disability despite medical treatment, as determined by a CRST score≥2 in any one of the items 16–23 from the Disability subsection of the CRST. 4) Stable medication for tremor for 30 days prior to study entry. |
