Table 2 Crude and adjusted hazard ratios of Parkinson’s disease for various cancers.
From: Longitudinal study of the inverse relationship between Parkinson’s disease and cancer in Korea
Incident rate per 1000 person-year | Incident rate difference per 1000 person-years (95% CI) | Hazard ratio for cancer (95% CI) | |||||||
|---|---|---|---|---|---|---|---|---|---|
PD | Control | Crudeb | P-value | Model 1b,c | P-value | Model 2b,c,d | P-value | ||
Overall cancer (n = 3165) | 11.52 | 14.09 | −2.57 (−3.82 to −1.32) | 0.82 (0.74–0.91) | <0.001a | 0.62 (0.56–0.68) | <0.001a | 0.63 (0.57–0.69) | <0.001a |
Gastric cancer (n = 689) | 2.70 | 2.95 | −0.25 (−0.82 to 0.32) | 0.91 (0.75–1.12) | 0.387 | 0.68 (0.56–0.84) | <0.001a | 0.69 (0.56–0.85) | <0.001a |
Thyroid cancer (n = 160) | 0.57 | 0.69 | −0.11 (−0.39 to 0.16) | 0.76 (0.49–1.17) | 0.216 | 0.58 (0.38–0.90) | 0.015a | 0.60 (0.39–0.93) | 0.022a |
Colorectal cancer (n = 637) | 1.98 | 2.81 | −0.83 (−1.37 to −0.28) | 0.71 (0.56–0.89) | 0.004a | 0.55 (0.44–0.70) | <0.001a | 0.56 (0.44–0.70) | <0.001a |
Lung cancer (n = 756) | 2.71 | 3.24 | −0.53 (−1.12 to 0.06) | 0.86 (0.71–1.06) | 0.153 | 0.69 (0.57–0.85) | <0.001a | 0.71 (0.58–0.87) | 0.001a |
Hepatic cancer (n = 364) | 1.26 | 1.57 | −0.31 (−0.72 to 0.10) | 0.83 (0.62–1.11) | 0.197 | 0.64 (0.47–0.86) | 0.003a | 0.64 (0.48–0.86) | 0.003a |
Bladder cancer (n = 194) | 0.69 | 0.83 | −0.14 (−0.44 to 0.16) | 0.86 (0.58–1.28) | 0.462 | 0.71 (0.48–1.06) | 0.091 | 0.71 (0.48–1.06) | 0.091 |
Pancreatic cancer (n = 201) | 0.45 | 0.91 | −0.46 (−0.77 to −0.16) | 0.50 (0.31–0.80) | 0.004a | 0.36 (0.22–0.58) | 0.001a | 0.37 (0.23–0.60) | 0.001a |
Gallbladder and biliary duct cancer (n = 201) | 0.88 | 0.82 | 0.05 (−0.25 to 0.36) | 1.07 (0.75–1.52) | 0.730 | 0.85 (0.59–1.23) | 0.389 | 0.87 (0.61–1.26) | 0.461 |
Kidney cancer (n = 92) | 0.52 | 0.35 | 0.17 (−0.03 to 0.38) | 1.41 (0.87–2.28) | 0.161 | 1.14 (0.70–1.85) | 0.606 | 1.14 (0.70–1.86) | 0.597 |
Hematological malignancy (n = 175) | 0.55 | 0.76 | −0.22 (−0.50 to 0.06) | 0.70 (0.45–1.08) | 0.109 | 0.56 (0.36–0.88) | 0.011a | 0.56 (0.36–0.87) | 0.010a |