Fig. 5: Relation between αSyn pathology in the retina/optic nerve and the LPC staging system. | npj Parkinson's Disease

Fig. 5: Relation between αSyn pathology in the retina/optic nerve and the LPC staging system.

From: α-Synuclein pathology in post-mortem retina and optic nerve is specific for α-synucleinopathies

Fig. 5: Relation between αSyn pathology in the retina/optic nerve and the LPC staging system.

Shown is the percentage of cases with αSyn pathology (dark green indicates presence, light green indicates absence) in the retina/optic nerve in different stages of α-synucleinopathy according to the LPC staging system. αSyn pathology in the retina/optic nerve was absent in cases without αSyn in the brain (non-αSyn) and with amygdala-only αSyn presence. Cases that did have αSyn pathology in the retina/optic nerve had an LPC stage of brainstem-predominant (67%), limbic (50%) or neocortical (82%). LPC Lewy pathology consensus criteria.

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