Fig. 3: Clinical characteristics of PD with GBA1 variants.

a Mean score of motor symptoms in N-PD, GBA1-PD, and L483P-PD. b AAO of N-PD, GBA1-PD, and L483P-PD. c Frequency (%) of family history and motor and non-motor symptoms in N-PD, GBA1-PD, and L483P-PD. * Significantly different between N-PD and GBA1-PD groups. † Significantly different between N-PD and L483P-PD groups. PD Parkinson’s disease; N-PD patients without GBA1 variant; GBA1-PD patients with GBA1 variants; L483P-PD patients with GBA1 p.L483P variant; AAO age at onset; UPDRS Unified Parkinson’s Disease Rating Scale; EDS excessive daytime sleepiness; pRBD probable rapid-eye-movement sleep behavior disorder; TD tremor-dominant; PIGD postural instability and gait difficulty; FOG Freezing of Gait.