Table 4 An overview of the literature about WM changes in PD using DKI and NODDI.

Kamagata et al.⁸⁵

PD patients

PD < Controls (MK and FA): anterior and posterior cingulum

Kamagata et al.⁸⁴

PD patients

PD < Controls (FA): anterior part of the inferior fronto-occipital fasciculus (IFOF), anterior SLF, and anterior and superior corona radiata; in part of the posterior SLF and in part of the genu and body of the corpus callosum: PD < Controls (MK): the SLF and inferior longitudinal fasciculus; the IFOF; the uncinate fasciculus; and the anterior, posterior, and superior corona radiata

Arab et al.⁸⁶

METH-treated animals

PD > Controls (FA): primary somatosensory cortex, fornix and ventral nucleus of the lateral lemniscus; PD > Controls (RK): in ventral nucleus of the lateral lemniscus and some of the lateral thalamic nuclei; PD < Controls (MD): in cingulum, external capsule and some of the lateral thalamic nuclei; PD < Controls (AD): cingulate cortex and external capsule; PD < Controls (RD): cingulum, primary somatosensory cortex, external capsule, some of the lateral thalamic nuclei and ventral nucleus of the lateral lemniscus

Khairnar et al.⁸⁸

TNWT-61 mice

PD > Controls (MK): the anterior and posterior part of the anterior commissure, in the internal capsule, left habenular commissure, medial lemniscus, mammillothalamic tract, external capsule, and reticular formation; PD > Controls (AK): the right-sided external capsule; PD < Controls (AD): ventral hippocampal commissure, trajection from/to septofimbrial nucleus, corpus callosum, external capsule, and in the fornix

Khairnar et al.⁸⁷

TNWT-61 mice

PD > Controls (MK): bilaterally in the external and internal capsule, anterior commissure (and in the posterior nerve part), lateral stripe of the striatum, diagonal band around the lateral septal nucleus and around the thalamus, mammillothalamic tract, fornix, cerebral peduncle, medial lemniscus, cingulum, reticular formation, medial longitudinal fasciculus, deep and intermediate white layers of the superior colliculus; corpus callosum, left-sided medial forebrain bundle, and brachium of the superior colliculus

Andica et al.⁸⁹

PD patients with neurocognitive and psychiatric disorders

PD-woNCPs > PDwNCPs (ICVF): Bilateral CST, cingulum hippocampus, IFOF, ILF, SLF, SLF temporal part, retrolenticular part of internal capsule, SCR, PCR, PTR, sagittal stratum, external capsule, tapetum; left PLIC; right ATR, CCG, UF; forceps major, body and splenium of corpus callosum; PD-wNCPs < Controls: Bilateral ATR, CST, CCG, cingulum hippocampus, IFOF, ILF, SLF, UF, SLF temporal part, ALIC, PLIC, retrolenticular part of internal capsule, ACR, SCR, PCR, PTR, sagittal stratum, external capsule, SFOF, and tapetum; forceps major and minor, genu, body, and splenium of corpus callosum

Ogawa et al.⁹⁰

PD patients with LID

PD wLID < PD woLID (ICVF): the external capsule, inferior fronto-occipital fasciculus, inferior longitudinal fasciculus, and uncinate fasciculus