Table 5 An overview of the literature about WM changes in PD using myelin imaging.
Study | Objective studied | MWF | MTR | MMS |
|---|---|---|---|---|
Dean III et al.92 | PD patients | PD > Controls: the thalamic radiations and posterior limb of the internal capsule, right centrumsemiovale encompassing superior longitudinal fasciculus, genu of corpus callosumand selected frontal and temporal regions, the body of the corpus callosum | ||
Baumeister et al.93 | PD patients with distinct clinical subtypes | Interhemispheric and long-range association fibers, projection fibers | ||
Morgen et al.96 | PD patients | PD < Controls: the paraventricular WM | ||
Tambasco et al.97 | PD patients | PD < Controls: the paraventricular WM | ||
Tambasco et al.98 | Mild and advanced PD patients | Advanced PD < Controls: frontal white matter, substantia nigra pars reticulata, periventricular white matter and parietal white matter; mild PD < Controls: substantia nigra pars reticulata, periventricular white matter and parietal white matter | ||
Hanyu et al.99 | PDD | PDD < Controls: frontal WM, genu of the corpus callosum | ||
Guan et al.101 | PD patients | PD < Controls: bilateral frontal deep WM; PD > Controls: Body of corpus callosum, bilateral External capsule, bilateral superior and inferior longitudinal fasciculus |
