Fig. 5: Genes from the PD-causal and PD-associated networks function within a subset of biological pathways. | npj Parkinson's Disease

Fig. 5: Genes from the PD-causal and PD-associated networks function within a subset of biological pathways.

From: Discovering genetic mechanisms underlying the co-occurrence of Parkinson’s disease and non-motor traits

Fig. 5

a The Venn diagram demonstrates the overlap of genes between the PD-causal network and PD-associated network identified across L0-L3. Comparatively, the number of intersecting genes is smaller when considering the size of each individual network. b Similarly, only ten biological pathways were found to overlap between the pathways enriched for PD-causal network genes and PD-associated network genes. c The figure shows the number of genes from each level of PD-causal and PD-associated networks enriched for each intersecting pathway. Of 10 intersecting pathways, seven (highlighted in grey) contain PD-risk genes.

Back to article page