Table 1 Demographic and clinical characteristics of study subjects
From: Gut microbiome is not associated with mild cognitive impairment in Parkinson’s disease
Characteristica | Control, N = 90b | PD-NC, N = 60b | PD-MCI, N = 58b | p-valuec | Control vs. PD-MCId | Control vs. PD-NCd | PD-NC vs. PD-MCId |
|---|---|---|---|---|---|---|---|
Female sex | 39 (43%) | 20 (33%) | 19 (33%) | 0.315 | |||
Constipation | 6 (6.7%) | 25 (42%) | 28 (48%) | <0.001 | |||
Age (years) | 68.9 (66.1, 72.5) | 71.3 (69.2, 74.9) | 73.1 (68.8, 77.9) | 0.002 | 0.001 | 0.078 | 0.162 |
MoCA | 28 (27, 29) | 28 (27, 29) | 23 (22, 25) | <0.001 | <0.001 | 0.777 | <0.001 |
Body mass index | 26.8 (24.1, 29.3) | 27.6 (24.1, 30.3) | 27.7 (25.3, 31.3) | 0.055 | 0.060 | 0.276 | 0.427 |
Years of education | 14 (11, 17) | 14 (12, 17) | 12 (10, 15) | 0.061 | 0.092 | 0.714 | 0.092 |
Caffeine use | 84 (93%) | 53 (88%) | 55 (95%) | 0.449 | |||
Spouse in current data | 7 (7.8%) | 4 (6.7%) | 1 (1.7%) | 0.309 | |||
Probiotics in last 6 months | 3 (3.3%) | 2 (3.3%) | 1 (1.7%) | >0.999 | |||
Antibiotics in last 6 months | 11 (12%) | 9 (15%) | 3 (5.2%) | 0.211 | |||
Vegan or vegetarian diet | 2 (2.2%) | 3 (5.0%) | 2 (3.4%) | 0.638 | |||
Years since PD diagnosis | 5 (3, 9) | 4 (2, 8) | 0.400 | ||||
Levodopa equivalent daily dosage (mg/day) | 475 (339, 806) | 472 (300, 874) | 0.988 | ||||
MDS-UPDRS III | 34 (21, 42) | 32 (26, 43) | 0.833 | ||||
Hoehn and Yahr stage | 2.00 (2.00, 2.50) | 2.00 (2.00, 2.50) | 0.978 |
