Table 3 DTI measures (AD, FA, MD, RD) of the WM tracts of the middle, superior, and inferior cerebellar peduncles in HS and early PD patients

From: Understanding the role of cerebellum in early Parkinson’s disease: a structural and functional MRI study

 

Early PD (mean ± SD)

HS (mean ± SD)

p value

AD

ICP

0.00122 ± 0.00003

0.00122 ± 0.00002

0.9721

MCP

0.00120 ± 0.00003

0.00119 ± 0.00004

0.0282

SCP

0.00118 ± 0.00003

0.00116 ± 0.00003

0.0035

FA

ICP

0.57039 ± 0.02536

0.62197 ± 0.03794

<0.001

MCP

0.61020 ± 0.01920

0.66239 ± 0.03254

<0.001

SCP

0.73918 ± 0.02747

0.76898 ± 0.02443

<0.001

MD

ICP

0.00076 ± 0.00003

0.00074 ± 0.00003

<0.001

MCP

0.00075 ± 0.00003

0.00078 ± 0.00004

<0.001

SCP

0.00078 ± 0.00003

0.00074 ± 0.00003

<0.001

RD

ICP

0.00054 ± 0.00003

0.00050 ± 0.00003

<0.001

MCP

0.00053 ± 0.00003

0.00048 ± 0.00004

<0.001

SCP

0.00057 ± 0.00003

0.00053 ± 0.00003

<0.001

  1. Differences between groups were assessed using the Mann–Whitney U test, FDR corrected for multiple comparisons. FDR-corrected p values as <0.05 is in bold.
  2. AD axial diffusivity, FA fractional anisotropy, MD mean diffusivity, RD radial diffusivity, SCP superior cerebellar peduncle, MCP middle cerebellar peduncle, ICP inferior cerebellar peduncle.
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