Table 4 Compartmental volume, iSD, MCS, and SBR side comparison based on nigrostriatal denervation

From: Analysis of striatal connectivity corresponding to striosomes and matrix in de novo Parkinson’s disease and isolated REM behavior disorder

 

Low SBR

High SBR

p-value

Cohen’s d

Putaminal SBR

1.77 ± 0.74

2.03 ± 0.69

<0.001

−1.26

Matrix-like volume

3.18 ± 0.80

3.01 ± 0.73

0.036

0.19

Matrix-like MCS

5319 ± 2733

5185 ± 2662

0.574

–

Matrix-like iSD

52.1 ± 9.0

51.1 ± 9.1

0.2

–

Striosome-like volume

0.98 ± 0.53

1.16 ± 0.61

0.004

−0.26

Striosome-like MCS

304 ± 387

389 ± 507

0.094

–

Striosome-like iSD

29.3 ± 12.3

32.0 ± 13.6

0.042

−0.18

  1. Using two-tailed paired samples t-test, n = 125. The results are shown as mean ± standard deviation, with volume values adjusted to the total striatal mask volume. Each item was tested as the side with higher putaminal specific binding ratio versus the side with lower putaminal specific binding ratio. Volumes are measured in cm3, iSDs in %, and MCSs are measured as a connectivity score.
  2. MCS mean connectivity score, iSD index of streamline density, SBR specific binding ratio.
  3. p < 0.05 values are highlighted in bold.
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