Fig. 2: GPi clinico-physiological correlates.

A Heatmap shows the Spearman rho correlations for GPi spiketrain features (firing rate, burst index, coefficient of variation, oscillatory power and burst dynamics across theta, alpha, low beta, and high beta frequencies) with clinical scores (total, tremor, rigidity, bradykinesia, and axial UPDRSIII OFF scores). Scatterplots show the top three spiketrain correlations with clinical scores based on the Spearman rho values. B Heatmap shows correlations of low and high beta GPi LFP power and burst dynamics with the aforementioned clinical scores, with scatterplots showing the highest LFP power and burst correlation with clinical scores based on Spearman rho values. Black squares indicate significant correlations (uncorrected for multiple comparisons). Asterisks denote Bayesian evidence in favor of the alternative hypothesis (* anecdotal, ** moderate).