Fig. 2: Effect of nigrostriatal degeneration and PPX on D1, D2 and D3 receptors expression in the DMS. | npj Parkinson's Disease

Fig. 2: Effect of nigrostriatal degeneration and PPX on D1, D2 and D3 receptors expression in the DMS.

From: Alpha-synuclein-induced nigrostriatal degeneration and pramipexole treatment disrupt frontostriatal plasticity

Fig. 2

A RNAscope in situ hybridization for D1 (top panel), D2 (middle panel) and D3 mRNA (bottom panel) at ×10 and ×40 magnifications. Scale bar = 20 µm. B Fluorescence intensity of D1 (left panel), D2 (middle panel), and D3 mRNA (right panel) in the DMS. GFP SALINE (N = 4); GFP PPX (N = 4); alpha-SYN SALINE (D1, D2: N = 4, D3: N = 5); alpha-SYN PPX (D1, D2: N = 4, D3: N = 5).

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