Fig. 6: Basal ganglia loops and their associated behaviors. | npj Parkinson's Disease

Fig. 6: Basal ganglia loops and their associated behaviors.

From: Alpha-synuclein-induced nigrostriatal degeneration and pramipexole treatment disrupt frontostriatal plasticity

Fig. 6

A Overview of motor, associative and limbic basal ganglia loops with their associated types of behaviors (top) and corresponding anatomy of the associative loop (blue) in human (left) and rat (right). B Disruption of cortico-striatal plasticity in motor and associative loops following degeneration of the substantia nigra pars compacta. AIC agranular insular cortex, BG basal ganglia, CMA cingulate motor area, DLS dorsolateral striatum, DMS dorsomedial striatum, IL infralimbic cortex, lOFC lateral orbitofrontal cortex, M1 primary motor cortex, PMC premotor cortex, PrL prelimbic cortex, SMA supplementary motor area, vmOFC ventromedial orbitofrontal cortex.

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